Summary
Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensations, perceptions, emotions, thoughts, and memories, and to observable motor and social behaviors. The research should be proposed as exploratory research and planning activities to establish feasibility and early-stage development that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent research project grant applications using invasive neural recording and stimulation technologies in the human brain. Projects should maximize opportunities to conduct innovative in vivo human neuroscience research made available by direct access to the brain from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs and by quantitative, mechanistic models where appropriate. Recipients will join a consortium working group, coordinated by the NIH, to identify consensus standards of practice, including neuroethical considerations, to collect and provide data for ancillary studies, and to aggregate and standardize data for dissemination among the wider scientific community.
Eligibility
- Nonprofits Non Higher Education Without 501c3
- County Governments
- Public and State Institutions of Higher Education
- Other
- For Profit Organizations Other Than Small Businesses
- City Or Township Governments
- Private Institutions of Higher Education
- Public and Indian Housing Authorities
- Small Businesses
- Nonprofits Having A 501(c)(3) Status With the Irs Other Than Institutions of Higher Education
- Native American Tribal Governments Federally Recognized
- Independent School Districts
- Native American Tribal Organizations Other Than Federally Recognized Tribal Governments
- State Governments
- Special District Governments
Funding categories
- Health
Official source and attribution
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