Summary
The purpose of this Notice of Funding Opportunity (NOFO) is to support SenNet Discovery and Validation Centers (SenNet DVCs) as a core component of Stage 2 of the NIH Common Fund Cellular Senescence Network (SenNet). Building on Stage 1 resources, DVCs will define, refine, and validate tissue- and disease-relevant cellular senescence signatures (“senotypes”) and associated biomarkers, and will investigate their functional consequences in human health and disease. DVCs are expected to generate and contribute high-quality molecular, cellular, and spatial datasets (including relevant metadata and documentation) and to use complementary experimental systems, as appropriate, to validate senotypes/biomarkers and characterize responses to senescence-associated perturbations or senotherapeutic approaches. DVC applications should also propose goals and aims for SenNet consortium-wide organizational and outreach activities (SenNet OOC functions).
Eligibility
- Special District Governments
- Nonprofits Having A 501(c)(3) Status With the Irs Other Than Institutions of Higher Education
- Small Businesses
- Other
- Native American Tribal Governments Federally Recognized
- Public and Indian Housing Authorities
- Native American Tribal Organizations Other Than Federally Recognized Tribal Governments
- State Governments
- Public and State Institutions of Higher Education
- Nonprofits Non Higher Education Without 501c3
- Private Institutions of Higher Education
- City Or Township Governments
- County Governments
- Independent School Districts
- For Profit Organizations Other Than Small Businesses
Funding categories
- Health
Official source and attribution
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