Summary
The purpose of the Somatic Mosaicism across Human Tissues (SMaHT) Network is to advance discovery of biological processes and disease mechanisms mediated by somatic mutations in human tissues. Since 2023, the program has generated multi-omic somatic mutation datasets from standardized human tissues spanning all three germ layers. Building on the Stage 1 foundation, the NIH intends to issue a Notice of Funding Opportunity (NOFO)supporting Stage 2 of the SMaHT Experimental and Computational Technology Development initiative. The Experimental and Computational Technology Development initiative supports multidisciplinary development, optimization, validation, benchmarking, and dissemination of rigorous, cost-effective technologies for somatic mutation detection and functional interpretation. Awardees will collaborate with other SMaHT Stage 2 initiatives to incorporate validated technologies into production workflows, pipelines, data releases, and community resources.
Eligibility
- For Profit Organizations Other Than Small Businesses
- State Governments
- Nonprofits Non Higher Education Without 501c3
- Special District Governments
- Native American Tribal Governments Federally Recognized
- Other
- Private Institutions of Higher Education
- County Governments
- Public and Indian Housing Authorities
- City Or Township Governments
- Small Businesses
- Independent School Districts
- Nonprofits Having A 501(c)(3) Status With the Irs Other Than Institutions of Higher Education
- Public and State Institutions of Higher Education
- Native American Tribal Organizations Other Than Federally Recognized Tribal Governments
Funding categories
- Health
Official source and attribution
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